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Projects & Publications



  1. HE-RO-IS strategic cooperation în Hematology, SEE 19-COP-0031
  2. Cooperation strategy for knowledge transfer, internationalization, and curricula innovation in the field of research education at the 3rd level of study (AURORA), SEE 21-COP-0049
  3. Strengthening the clinical approach to haemophilia in the northern region of Romania and developing a national register


  1. Supporting a team of young researchers în creating an independent research program based on the Sleeping Beauty protocol to develop CAR T cells, SEATTLE, TE 139/2020 (PN-III-P1-1.1-TE-2019-0271)
  2. Next generation preclinical model for evaluation of microRNA-205-5p therapeutic role în limitation of melanoma metastasis, MELAMIR, PD 122 (PN-III-P1-1.1-PD-2019-0805)
  3. Validation of epigenetic reprogramming of lung cancer models and anti-cancer activity through serial administration of repositioned 5-Azacytidine, AZUR (PN-III-P4-ID-PCE-2020-1957)
  4. Harnessing the Ubiquitin-Proteasome System (UPS) to Suppress Tumors’ Growth via Manipulating Generation of NF-κB, ROME, (PN-III-P4-ID-PCE-2020-2252)
  5. The role of CYP26 in retinoid homeostasis against the background of etiopathogenesis and treatment response for myelodysplastic syndromes, LONDON (PN-III-P4-ID-PCE-2020-1957)
  6. Transfer of knowledge in clinical applications of biogenomics in oncology and related fields – BIOGENONCO” ID P_40_318, in Subsidiary Contract no. 28781/23.09.2020 “Evaluation of the antitumor action and optimization of the composition of the product Nera Plant Vito-complex”
  7. Advanced preclinical validation of microRNA-205-5p-based therapeutic model for inhibition of epithelial to mesenchymal transition în melanoma metastasis MELAMET, 539PED (PN-III-P2-2.1-PED-2019-3640)
  8. Potential protein biomarkers with utility in the diagnosis of intrahepatic cholangiocarcinoma. PD113/2020 (PN-III-P1-1.1-PD2019-0852)
  9. Stereoselective technologies applicable in the metabolomics of neurological and neurodegenerative diseases – (PN-III-P1-1.1-. PD-2019-0929)


  1. Pralea IE, Moldovan RC, Țigu AB, Petrache AM, Hegheș SC, Mitoi M, Cogălniceanu G, Iuga CA. Profiling of Polyphenolic Compounds of Leontopodium alpinum Cass Callus Cultures Using UPLC/IM-HRMS and Screening of In Vitro Effects. Plants (Basel).2022 January.Q1, IF=3.935
  2. Lucaciu LA, Ilieș M, Vesa ȘC, Seicean R, Din S, Iuga CA, Seicean A. Serum Interleukin (IL)-23 and IL-17 Profile in Inflammatory Bowel Disease (IBD) Patients Could Differentiate between Severe and Non-Severe Disease. Journal of Personalized Medicine. 2021 November. Q1. IF=4.945
  3. Stiufiuc GF, Toma V, Onaciu A, Chiș V, Lucaciu CM, Știufiuc RI. Proving Nanoscale Chiral Interactions of Cyclodextrins and Propranolol Enantiomers by Means of SERS Measurements Performed on a Solid Plasmonic Substrate. Pharmaceutics (MDPI). 2021 October. Q1. IF: 6.321.
  4. Dirzu N, Hotea I, Jitaru C, Brinza M, Urian L, Peters MC, Gal K, Popescu L, Blag C, Marian M, Pal E, Stanescu M, Cenariu D, Tarniceriu C, Serban M, Dima D, Coriu D, Tomuleasa C. Mobile Health Technology for the Personalized Therapy of Hemophilia. Frontiers in Medicine (Lausanne). 2021 September. Q1. IF=5.09.
  5. Moldovan CS, Onaciu A, Toma V, Marginean R, Moldovan A, Tigu AB, Stiufiuc GF, Lucaciu CM, Stiufiuc RI. Quantifying Cytosolic Cytochrome c Concentration Using Carbon Quantum Dots as a Powerful Method for Apoptosis Detection. Pharmaceutics. 2021 September, Q1. IF: 6.321.
  6. Moisoiu V, Sas V, Stefancu A, Iancu SD, Jurj A, Pasca S, Iluta S, Zimta AA, Tigu AB, Teodorescu P, Turcas C, Blag C, Dima D, Popa G, Arghirescu S, Man S, Colita A, Leopold N and Tomuleasa C. SERS-Based Evaluation of the DNA Methylation Pattern Associated with Progression in Clonal Leukemogenesis of Down Syndrome. Frontiers in Bioengineering and Biotechnology. 2021 July.Q1. IF 5.890.
  7. Stefancu A, Moisoiu V, Desmirean M, Iancu SD, Tigu AB, Petrushev B, Jurj A, Cozan RG, Budisan L, Fetica B, Roman A, Turcas C, Dobrie G, Zdrenghea M, Teodorescu P, Pasca S, Piciu D, Dima D, Balint Z, Leopold N, Tomuleasa C. SERS-based DNA methylation profiling allows the differential diagnosis of malignant lymphadenopathy. Spectrochimica Acta Part A- Molecular and Biomolecular Spectroscopy. 2021 July. Q1 – Spectroscopy. IF 4.098.
  8. Zimta AA, Hotea I, Brinza M, Blag C, Iluta S, Constantinescu C, Bashimov A, Marchis-Hund EA, Coudsy A, Muller-Mohnssen L, Dirzu N, Gulei D, Dima D, Serban M, Coriu D, Tomuleasa C. The Possible Non-Mutational Causes of FVIII Deficiency: Non-Coding RNAs and Acquired Hemophilia A. Frontiers in Medicine (Lausanne). 2021 April. Q1. IF=3.9.
  9. Țigu AB, Moldovan CS, Toma VA, Farcaș AD, Moț AC, Jurj A, Fischer-Fodor E, Mircea C, Pârvu M. Phytochemical Analysis and In Vitro Effects of Allium fistulosum L. and Allium sativum L. Extracts on Human Normal and Tumor Cell Lines: A Comparative Study, Molecules, 2021 February, Q2 Chemistry. IF: 4.411.
  10. Tefas C, Mărginean R, Toma V, Petrushev B, Fischer P, Tanțău M, Știufiuc R. Surface-enhanced Raman scattering for the diagnosis of ulcerative colitis: will it change the rules of the game? Analytical and Bioanalytical Chemistry. 2021 January. Q1. IF: 4.14.
  11. Ilies M, Uifalean A, Pasca S, Dhople VM, Lalk M, Iuga CA, Hammer E. From Proteomics to Personalized Medicine: The Importance of Isoflavone Dose and Estrogen Receptor Status in Breast Cancer Cells. Journal of Personalized Medicine, 2020 December. Q1. IF=4.43.
  12. Pralea IE, Moldovan RC, Țigu AB, Ionescu C, Iuga CA. Mass Spectrometry-Based Omics for the Characterization of Triple-Negative Breast Cancer Bio-Signature. Journal of Personalized Medicine. 2020 December, Q1 – Medicine, general & internal. IF: 4.945.