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WHY US

State of the Art Technologies
and Highly Qualified Team

OUR TEAM

Why MEDFUTURE?

We come to you as a partner rather than a service provider and we guarantee:

  • Scientific excellence – highly trained team members
  • Available capacity of highly specialized research infrastructure
  • Flexibility – we could offer, on demand, a personalized design of our services
  • Complete services – we provide to our customers a complete range of specific research services
  • Highly reliable results – we guarantee the quality of our services
  • Orientation towards the clients – we focus to understand customers’ perceptions and expectations

Our areas of research interest are covering:

Synthesis and physico-chemical characterization of different types of multifunctional nanostructures and development of new imaging strategies on nanostructures and various biological samples.

Development of target therapies, diagnostic and prognostic tools and assessment of clinically relevant biomarkers with role in new targeted therapies, early diagnosis or prognosis.

High-resolution mass spectrometry (HRMS) based biomarker discovery towards precision medicine by employing: targeted and untargeted proteomics and/or metabolomics.

Development of preclinical animal models (immunocompromised or transgenic mice), preclinical evaluation of novel drugs and therapeutic combinations, imaging techniques (IVIS, mRI).

Meet our team

Our highly trained and dedicated team who has completed or ongoing doctoral studies, conducts their own postdoctoral research projects and are involved in multiple multidisciplinary research projects coordinated by members of scientific community.

Cristina-Adela Iuga, PhD
Cristina-Adela Iuga, PhDFaculty of Pharmacy (1995), Applied Pharmaceutical Sciences Master (2001), Habilitation Pharmaceutical Sciences (2019)
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Professor
Director of Research Center for Advanced Medicine – MEDFUTURE
Coordinator of the Department of Proteomics and Metabolomics
Expertise
: coordination of scientific projects that involve development, optimization and application of ‘omics’- mass spectrometry-based technologies (proteomics and metabolomics), for the development of diagnostic and therapeutic signatures, specific biomarker discovery and validation in the context of translational and personalized medicine.
Publons Google Academic
Maria Ilieș, PhD
Maria Ilieș, PhDFaculty of Pharmacy (2013), Applied Pharmaceutical Sciences Master (2014), PhD (2017)
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Scientific Researcher
Department of Proteomics and Metabolomics
Expertise
: elaboration and application of specific protocols to the analysis of proteins from various biospecimen through advanced techniques of proteomics and mass spectrometry with the purpose of identifying and quantifying them and assigning them a potential role of biomarker in clinical practice.
Publons Google Academic
Radu-Cristian Moldovan, PhD
Radu-Cristian Moldovan, PhDFaculty of Pharmacy (2013); PhD degree (2018)
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Scientific Researcher
Department of Proteomics and Metabolomics
Expertise
: development and validation of separative techniques (LC, CE, GC) coupled with mass spectrometry for metabolomics; development and application of sample preparation techniques for metabolomics; chiral analysis; chiral metabolomics; data analysis for biomarker discovery.
Publons Google Academic
Ioana-Ecaterina Pralea, PhD Student
Ioana-Ecaterina Pralea, PhD StudentFaculty of Pharmacy (2015), Applied Pharmaceutical Sciences Master (2020), PhD student (2016)
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Pharmacist
Department of Proteomics and Metabolomics
Expertise
: samples preparation of paraffined tissues, cell culture, serum/plasma for mass spectrometry analysis. Non-separative techniques: MALDI-MS, UV-VIS, FLD; Separative techniques: LC-MS - untargeted proteomics and metabolomics. Cell cultures for proteome and metabolome analysis by mass spectrometry.
Publons Google Academic
Diana (Gulei) Tomuleasa, PhD
Diana (Gulei) Tomuleasa, PhDFaculty of Biology (2014), Molecular Biotechnologies Master (2016), PhD (2019)
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Scientific Researcher
Coordinator of the Department of In Vivo Studies - Animal Facility
Expertise
: development and application of protocols specific to the preclinical research sector at in vitro and in vivo level, especially regarding the mechanisms of cellular signaling in the malignant cell, new diagnostic and prognostic biomarkers and new therapeutic instruments.
Publons Google Academic
Raluca Munteanu, PhD Student
Raluca Munteanu, PhD StudentFaculty of Biology (2014), PhD Student (2019)
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Biologist
Department in Vivo Studies - Animal Facility
Expertise
: development of advanced murine models for preclinical studies, including patient-derived xenografts (PDX) models. Experimental animal microsurgery, in vivo imaging methods (IVIS, MRI), sample processing and collection and ex vivo samples handling, data interpretation.
Publons Google Academic
Richard-Ionuț Feder
Richard-Ionuț FederFaculty of Biology (2020)
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Biologist
Department in Vivo Studies - Animal Facility
Expertise
: implementation of minimally and medium invasive protocols at in vivo level, handling and monitorization of small animals, imaging techniques (IVIS), hematology analysis, collection of biological samples and data interpretation.
Publons Google Academic
Ciprian Tomuleasa, MD, PhD
Ciprian Tomuleasa, MD, PhDFaculty of Medicine (2011), PhD (2013), Habilitation Medical Sciences (2017)
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Scientific Researcher
Coordinator of the Department of Translational Medicine
Expertise
: development and application of basic and translational research protocols in the area of oncological hematology, including immunotherapy, mechanisms of drug resistance and new tools for assessing the persistence of minimal residual disease.
Publons Google Academic
Diana Cenariu, PhD
Diana Cenariu, PhDFaculty of Horticulture (2006), PhD (2013)
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Scientific researcher
Department of Translational Medicine
Expertise
: tumor and non-tumor cell cultures; evaluation of the in vitro effect for various therapeutic compounds; determination of the degree of cell death by flow cytometry. Processing and storage of blood samples, maintaining the biobank of biological samples. Determination of the degree of methylation of DNA and evaluation of gene expression by RT-PCR.
Publons Google Academic
Adrian Bogdan Țigu, PhD
Adrian Bogdan Țigu, PhDFaculty of Biology (2014), PhD (2021)
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Biologist
Department of Translational Medicine
Expertise
: obtaining culture of tumor and non-tumor cells; evaluation of the in vitro effect of bioactive compounds; determination of the degree of cell death by flow cytometry, microscopic determinations and evaluation of proteins in WesternBlot and ELISA. Processing and storing blood samples, maintaining the biobank of biological samples. Determination of the methylation degree of DNA and evaluation of gene expression by RT-PCR.
Publons Google Academic
Alina-Andreea Zimța-Pîrvu, PhD Student
Alina-Andreea Zimța-Pîrvu, PhD Student Faculty of Biology (2015), PhD Student (2018)
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Biologist
Department of Translational Medicine
Expertise
: cell culture maintenance, in vitro assays of cell viability, invasion and migration, cell preparation for imaging, evaluation of gene expression through real-time PCR, protein determination through Western Blot, processing and maintaining the biobank of biological samples. Basic knowledge of data analysis through R language programming.
Publons Google Academic
Rareș-Ionuț Știufiuc, PhD
Rareș-Ionuț Știufiuc, PhDFaculty of Physics (2001), Condensed Matter Physics Master (2002), PhD (2005), Applied Pharmaceutical Sciences Master (2010), Habilitation Pharmaceutical Sciences (2017)
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Professor
Coordinator of the Department of NanoBioPhysics
Expertise
: Development of new types of multifunctional nanostructures (plasmonic, magnetic, magnetoplasmonic, hybrid liposomes, quantum dots) for different biomedical applications. Development of new strategies for early disease detection by means of ultrasensitive vibrational analysis combined with multivariate analysis of spectra collected on different biological samples; investigation of nanoscale interactions of different molecular species by using state of the art techniques.
Publons Google Academic
Valentin Toma, PhD
Valentin Toma, PhDFaculty of Physics (2001), Condensed Matter Physics Master (2002), PhD (2007)
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Physicist
Department of NanoBioPhysics
Expertise
: Synthesis and characterization of nano-objects with biomedical applications. Syntheses of SERS-colloidal and solid plasmonic substrates based on nanoparticles. Raman vibrational spectroscopy/SERS. AFM surface spectroscopy. Data processing.
Publons Google Academic
Cristian Silviu Moldovan, PhD Student
Cristian Silviu Moldovan, PhD StudentFaculty of Biology (2016), Molecular Biotechnology Master (2018), PhD Student (2018)
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Biologist
Department of NanoBioPhysics
Expertise
: Synthesis and physico-chemical characterization of nanoparticles; fluorescence optical microscopy and dark field microscopy. Fluorescence confocal microscopy and sample preparation; Development and optimization of fluorescent labeling protocols for biological molecules /cellular structures and semi-quantitative analysis based on fluorescence.
Publons Google Academic
Anca (Onaciu) Ghenț, PhD Student
Anca (Onaciu) Ghenț, PhD StudentFaculty of Biology (2014), Molecular Biotechnology Master (2016), PhD Student (2020)
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Biotechnology Engineer
Department of NanoBioPhysics
Expertise
: Synthesis and characterization of nanostructures; Functionalization of nanostructures; Experimental in vitro and in vivo studies; Biological and non-biological samples processing for analysis (confocal microscopy, fluorescence microscopy, dark field microscopy, Raman/SERS spectroscopy, transmission electron microscopy).
Publons Google Academic
Noemi Dîrzu, MD, PhD Student
Noemi Dîrzu, MD, PhD StudentFaculty of Medicine (2005), Laboratory Medicine Residency (2014)
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Laboratory physician
Department of Clinical Studies Support
Expertise
: Stem cell and tumor cultures, in vitro chemo- and radiosensitivity tests, isolation, differentiation and characterization of stem cells of human and animal origin, isolation and characterization of tumor stem cells, biocompatibility and cytotoxicity tests, immunological tests. Functionalization of implantable biomaterials and its in vitro testing. Laboratory diagnosis of bleeding disorders.
Publons Google Academic
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IN VIVO

In Vivo Studies – Animal Facility Department

The In vivo Studies – Animal Facility Department provides the opportunity to use advanced animal models needed to implement preclinical research projects to develop targeted therapeutic strategies and minimally invasive diagnostic/prognostic methods.

The Department is unique at national level in terms of infrastructure and hosts state-of-the-art imaging equipment – MRI and IVIS for highly refined in vivo imaging investigations.

The laboratory animal housing space is also under strict sterility control to create an aseptic environment necessary for advanced animal models with severe immunocompromised or genetically modified phenotype.

NANOBIOPHYSICS

NanoBioPhysics Department

The NanoBioPhysics Department has an interdisciplinary structure addressing highly topical scientific issues in biomedicine and biotechnology.

The department has state-of-the-art equipment allowing both the synthesis and fully physico-chemical characterisation of different types of hybrid multifunctional nanostructures (plasmonic, magnetic, magnetoplasmonic, liposomal, polymeric nanoparticles, carbon quantum dots, etc.) and the investigation at the nanoscale of their interactions with different molecules or biological environments.

'OMICS'

Proteomics and Metabolomics Department

The Proteomics and Metabolomics Department exploits advanced sample preparation workflow and high-resolution mass spectrometry (LC-QTOF-IMS, ICP-MS, GC-MS) to achieve protein and metabolites profiling of a wide range of specimens – serum, plasma, fresh frozen tissue, paraffin-embedded tissue (FFPE), cell culture lysates, a unique proteomic and metabolomic platform in Romania.

TRANSLATIONAL

Translational Medicine Department

The Translational Medicine Department provides comprehensive experimental cell culture and in vitro functional assays, as well as molecular assays at the DNA, RNA and protein level.

Specifically, the department supports cell line expansion, cryopreservation for cell banking, in vitro testing of active compounds and evaluation of their efficacy through cytotoxicity assays, imaging evaluations and enzyme-linked immunosorbent assays.

Changes at the molecular level are quantified by PCR, RT-qPCR and Western Blot assays.

CLINICAL STUDIES SUPPORT

Clinical Studies Support Department

The Clinical Studies Support Department is the newest department in the center.

The Haemostasis Laboratory is dedicated to the diagnosis and monitoring of haemophilic patients in the North-West part of Romania. It is providing several medical services fot this pathology:

  • Factor VIII plasma level assay
  • Factor VIII inhibitors plasma level assay
  • Emicizumab plasma level assay